Old meets new: ancient “cupping” method boosts covid vaccines 新旧碰撞：传统“拔罐”加强新冠疫苗吸收
Pressing a suction cup to the skin to boost health may sound like pseudoscience.
And to some scientists, “cupping” is just that: a form of quackery akin to acupuncture and bloodletting.
But researchers reporting in the journal Science Advances have applied the ancient technique to covid-19 vaccine delivery with success.
In experiments, rats were injected with pure SARS-CoV-2 DNA, which on its own quickly degrades in the body.
在实验中，单独注射SARS-CoV-2 DNA的小鼠，SARS-CoV-2 DNA在体内迅速就降解。
But following up the injection with moderate suction through a plastic cup induced the skin cells to absorb the DNA, triggering an immune response 100 times stronger than injection alone.
Based on these results, cupping has been incorporated into DNA-vaccine clinical trials.
These matter hugely because DNA vaccines, such as India’s ZyCoV-D, do not require constant refrigeration, and so are easier to roll out in poor countries.
This goes to show that scientists should take inspiration wherever they can get it; public health is no place for squeamishness.